Marine source has gained importance in the pharmaceutical field from ancient time onwards as pharmaceutical adjuvant. But now marine environment has proven to be a very rich source of potent compound that has demonstrated significant activities against cancer, inflammation, pain, allergy and human pathogens. But it’s fascinated to know that this unique animal; sponge contains numerous microorganisms that led to the discovery of many antibiotics. Nowadays, researchers have focused on antibacterial activity of marine products since the microorganism became resistant after long use to a synthetic antibiotic. In view of this we have selected marine algae (Ulva reticulata) as the model for antibacterial studies. The bioactive principles were extracted from green algae by continuous hot percolation method using methanol and petroleum ether as solvent for 4 hours. The petroleum ether extracts of green algae showed the presence of various constituents such as carbohydrates, glycosides, proteins, tannins, flavanoids and alkaloids. The spectrum of antibacterial studies were carried out by agar well diffusion technique against B.subtilis MTCC 121, E.coli MTCC 405, S.pyogenes MTCC 442 and S. aureus MTCC 96 and the activity was well compared with standard Ciproflaxacin drug (5µg/disc). The results have shown that all the extracts were effective against E.coli and S. pyogenes when compared to the rest. Hence this preliminary study infers that the potent antibacterial substances can be isolated against various bacterial pathogens.
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